Monthly Archives: February 2019

New Preprint: Modelling the interaction between RyR and IP3R calcium release in cardiomyocytes

Calcium signalling plays a central role in heart cells. With each heart beat, calcium is released from intracellular stores (SR) via RyR channels to trigger contraction. However, calcium signalling is also implicated in controlling the growth of heart cells, as … Continue reading

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New Preprint: Development of a 3D computational model of calcium release in heart cells

Our new preprint on bioRXiv describes the development of a structurally realistic 3D computational model of a cardiomyocyte which we use to simulate reaction-diffusion of calcium release from RyR clusters during the initial phase of the cardiac calcium transient. We use … Continue reading

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