Many congratulations to Claire, who has now successfully completed her PhD.
Claire’s thesis ‘Understanding the Regulation of Epidermal Tissue Structure by Molecular and Cellular Processes Using Multi-Scale Models’ was supervised by Dr James Osborne and Prof. Edmund Crampin. In her thesis, Claire built a multi-cellular computational model of the epidermis — the outer-most layer of the skin — to understand how epidermal height is regulated. Her study established how balance between cell-signalling, proliferation and removal maintains the epidermal thickness in healthy tissue, and also provided insight into the effects of diseases which diminish the protective role of the tissue.
Claire is now a postdoctoral fellow at the University of Amsterdam (UvA) working with Prof Alfons Hoekstra’s Computational Science Lab, as a part of the INSIST ‘in silico stroke trials’ project.